Data / Rankings / Depression in adults, local model estimate / Cities in South Carolina

Cities in South Carolina by depression in adults, local model estimate

Clemson, SC had the highest depression in adults, local model estimate of 43 cities in 2022, at 25.9%. Hilton Head Island, SC had the lowest, at 16.7%. The median was 21.1%. Source: the Centers for Disease Control and Prevention.

Keep it in a collection in your library.
Highest25.9Clemson, SC
Lowest16.7Hilton Head Island, SC
Median21.143 cities

All cities, 2022

Clemson, SC: 25.9 %Clemson, SC25.9Anderson, SC: 24.1 %Anderson, SC24.1Spartanburg, SC: 23.9 %Spartanburg, SC23.9Conway, SC: 23.5 %Conway, SC23.5Greenwood, SC: 23.5 %Greenwood, SC23.5Greer, SC: 23.2 %Greer, SC23.2Columbia, SC: 22.7 %Columbia, SC22.7Fountain Inn, SC: 22.7 %Fountain Inn, SC22.7Greenville, SC: 22.7 %Greenville, SC22.7Hanahan, SC: 22.7 %Hanahan, SC22.7Goose Creek, SC: 22.4 %Goose Creek, SC22.4Simpsonville, SC: 22.4 %Simpsonville, SC22.4Easley, SC: 22.3 %Easley, SC22.3Moncks Corner, SC: 22.3 %Moncks Corner, SC22.3Summerville, SC: 22 %Summerville, SC22Charleston, SC: 21.7 %Charleston, SC21.7Mauldin, SC: 21.7 %Mauldin, SC21.7Cayce, SC: 21.6 %Cayce, SC21.6Newberry, SC: 21.6 %Newberry, SC21.6Gaffney, SC: 21.4 %Gaffney, SC21.4Myrtle Beach, SC: 21.1 %Myrtle Beach, SC21.1North Augusta, SC: 21.1 %North Augusta, SC21.1Sumter, SC: 21 %Sumter, SC21North Charleston, SC: 20.9 %North Charleston, SC20.9Port Royal, SC: 20.7 %Port Royal, SC20.7Forest Acres, SC: 20.5 %Forest Acres, SC20.5Mount Pleasant, SC: 20.5 %Mount Pleasant, SC20.5York, SC: 20.3 %York, SC20.3Irmo, SC: 20.2 %Irmo, SC20.2West Columbia, SC: 20.2 %West Columbia, SC20.2Hardeeville, SC: 19.8 %Hardeeville, SC19.8Rock Hill, SC: 19.8 %Rock Hill, SC19.8Bluffton, SC: 19.7 %Bluffton, SC19.7Florence, SC: 19.7 %Florence, SC19.7James Island, SC: 19.7 %James Island, SC19.7Aiken, SC: 19.6 %Aiken, SC19.6Fort Mill, SC: 19.5 %Fort Mill, SC19.5Lexington, SC: 19.3 %Lexington, SC19.3Orangeburg, SC: 19.2 %Orangeburg, SC19.2Beaufort, SC: 19.1 %Beaufort, SC19.1North Myrtle Beach, SC: 19 %North Myrtle Beach, SC19Tega Cay, SC: 18.5 %Tega Cay, SC18.5Hilton Head Island, SC: 16.7 %Hilton Head Island, SC16.7Clemson, SC: 25.9 %Clemson, SC25.9Anderson, SC: 24.1 %Anderson, SC24.1Spartanburg, SC: 23.9 %Spartanburg, SC23.9Conway, SC: 23.5 %Conway, SC23.5Greenwood, SC: 23.5 %Greenwood, SC23.5Greer, SC: 23.2 %Greer, SC23.2Columbia, SC: 22.7 %Columbia, SC22.7Fountain Inn, SC: 22.7 %Fountain Inn, SC22.7Greenville, SC: 22.7 %Greenville, SC22.7Hanahan, SC: 22.7 %Hanahan, SC22.7Goose Creek, SC: 22.4 %Goose Creek, SC22.4Simpsonville, SC: 22.4 %Simpsonville, SC22.4Easley, SC: 22.3 %Easley, SC22.3Moncks Corner, SC: 22.3 %Moncks Corner, SC22.3Summerville, SC: 22 %Summerville, SC22Charleston, SC: 21.7 %Charleston, SC21.7Mauldin, SC: 21.7 %Mauldin, SC21.7Cayce, SC: 21.6 %Cayce, SC21.6Newberry, SC: 21.6 %Newberry, SC21.6Gaffney, SC: 21.4 %Gaffney, SC21.4Myrtle Beach, SC: 21.1 %Myrtle Beach, SC21.1North Augusta, SC: 21.1 %North Augusta, SC21.1Sumter, SC: 21 %Sumter, SC21North Charleston, SC: 20.9 %North Charleston, SC20.9Port Royal, SC: 20.7 %Port Royal, SC20.7Forest Acres, SC: 20.5 %Forest Acres, SC20.5Mount Pleasant, SC: 20.5 %Mount Pleasant, SC20.5York, SC: 20.3 %York, SC20.3Irmo, SC: 20.2 %Irmo, SC20.2West Columbia, SC: 20.2 %West Columbia, SC20.2Hardeeville, SC: 19.8 %Hardeeville, SC19.8Rock Hill, SC: 19.8 %Rock Hill, SC19.8Bluffton, SC: 19.7 %Bluffton, SC19.7Florence, SC: 19.7 %Florence, SC19.7James Island, SC: 19.7 %James Island, SC19.7Aiken, SC: 19.6 %Aiken, SC19.6Fort Mill, SC: 19.5 %Fort Mill, SC19.5Lexington, SC: 19.3 %Lexington, SC19.3Orangeburg, SC: 19.2 %Orangeburg, SC19.2Beaufort, SC: 19.1 %Beaufort, SC19.1North Myrtle Beach, SC: 19 %North Myrtle Beach, SC19Tega Cay, SC: 18.5 %Tega Cay, SC18.5Hilton Head Island, SC: 16.7 %Hilton Head Island, SC16.7
%. Source: CDC, PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCities2022 (%)Change on 2021
1Clemson, SC25.9+0.4 pts
2Anderson, SC24.1+2.1 pts
3Spartanburg, SC23.9+1.1 pts
4Conway, SC23.5+0.1 pts
4Greenwood, SC23.5+2.3 pts
6Greer, SC23.2+1.5 pts
7Columbia, SC22.7+0.1 pts
7Fountain Inn, SC22.7+1.4 pts
7Greenville, SC22.7+3 pts
7Hanahan, SC22.7+2.7 pts
11Goose Creek, SC22.4+2.3 pts
11Simpsonville, SC22.4+2.4 pts
13Easley, SC22.3-1.1 pts
13Moncks Corner, SC22.3+2.7 pts
15Summerville, SC22+0.2 pts
16Charleston, SC21.7+1.3 pts
16Mauldin, SC21.7+2 pts
18Cayce, SC21.6-1.9 pts
18Newberry, SC21.6+0.2 pts
20Gaffney, SC21.4+0.6 pts
21Myrtle Beach, SC21.1-1.2 pts
21North Augusta, SC21.1-0.1 pts
23Sumter, SC21+0.2 pts
24North Charleston, SC20.9+0.4 pts
25Port Royal, SC20.7+1 pts
26Forest Acres, SC20.5+1 pts
26Mount Pleasant, SC20.5+1.3 pts
28York, SC20.3-0.8 pts
29Irmo, SC20.2-1.4 pts
29West Columbia, SC20.2-2.9 pts
31Hardeeville, SC19.8-1.1 pts
31Rock Hill, SC19.8-2 pts
33Bluffton, SC19.7+1.1 pts
33Florence, SC19.7-0.4 pts
33James Island, SC19.7+0.7 pts
36Aiken, SC19.6+0.3 pts
37Fort Mill, SC19.5-1.6 pts
38Lexington, SC19.3-3.4 pts
39Orangeburg, SC19.2-0.2 pts
40Beaufort, SC19.1+0.1 pts
41North Myrtle Beach, SC19-1 pts
42Tega Cay, SC18.5-1 pts
43Hilton Head Island, SC16.7+0.9 pts

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the cities are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence (Cities in South Carolina by depression in adults, local model estimate, 2022) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence, Cities in South Carolina by depression in adults, local model estimate, 2022. Centers for Disease Control and Prevention, 12 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-cities?period=2022. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence. Cities in South Carolina by depression in adults, local model estimate, 2022. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-cities?period=2022.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence, Cities in South Carolina by depression in adults, local model estimate, 2022 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-cities?period=2022 (Accessed: 12 October 2026).

BibTeX
@misc{centers_cities_in_south_carolina_2022,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence: Cities in South Carolina by depression in adults, local model estimate, 2022}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-cities?period=2022. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence: Cities in South Carolina by depression in adults, local model estimate, 2022
PY  - 2025
DA  - 2025/12/12
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-cities?period=2022
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-cities?period=2022.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  -
Embed this chart

Paste this code into a web page or a blog post. The chart shows the latest figures as they are published, with the source and a link back to this page.

Sites that read oEmbed links, such as WordPress, can show the chart when you paste the link to this page.

Use this data in your AI agent

Invokely serves this figure to AI assistants through MCP and to code through a REST API, with the source and citation attached. Ask your assistant:

Rank Cities in South Carolina by depression in adults, local model estimate using official data, and cite the source.
rank_places {"indicator":"adult_depression_rate_modelled","level":"municipality","within":"South Carolina","limit":10}
GET https://invokely.ai/api/v1/rank?indicator=adult_depression_rate_modelled&level=municipality&within=South%20Carolina&limit=10

Connect Claude, ChatGPT or Cursor in one step. The trial answers 25 calls a day without an account.

Questions

Which city has the highest depression in adults, local model estimate?

Clemson, SC, with 25.9% in 2022, according to the Centers for Disease Control and Prevention.

Which city has the lowest depression in adults, local model estimate?

Hilton Head Island, SC, with 16.7% in 2022.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, Place Data (eav7-hnsx, sd8v-uq83, krqc-563j and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Cities in South Carolina: more rankings