Counties in Mississippi by depression in adults, local model estimate, 2023

Tishomingo County had the highest depression in adults, local model estimate of 82 counties in 2023, at 22.2%. Jefferson County had the lowest, at 16.5%. The median was 19.4%. Source: the Centers for Disease Control and Prevention.

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Median19.482 counties

Map of counties, 2023

Adams County: 17.4 %Alcorn County: 21.9 %Amite County: 19 %Attala County: 18.8 %Benton County: 19.4 %Bolivar County: 18.9 %Calhoun County: 20 %Carroll County: 18.6 %Chickasaw County: 19.1 %Choctaw County: 19.2 %Claiborne County: 17.5 %Clarke County: 20.2 %Clay County: 18.1 %Coahoma County: 17.9 %Copiah County: 18.9 %Covington County: 19.2 %DeSoto County: 19.7 %Forrest County: 20.8 %Franklin County: 19.6 %George County: 21.6 %Greene County: 19.8 %Grenada County: 19.2 %Hancock County: 19.7 %Harrison County: 21.1 %Hinds County: 17.3 %Holmes County: 17.9 %Humphreys County: 18.6 %Issaquena County: 16.8 %Itawamba County: 21.1 %Jackson County: 19.7 %Jasper County: 18.1 %Jefferson County: 16.5 %Jefferson Davis County: 17.8 %Jones County: 19.9 %Kemper County: 17.3 %Lafayette County: 20.5 %Lamar County: 21.3 %Lauderdale County: 18.8 %Lawrence County: 20.6 %Leake County: 19.2 %Lee County: 20.1 %Leflore County: 17.6 %Lincoln County: 19.8 %Lowndes County: 19 %Madison County: 17.7 %Marion County: 20.4 %Marshall County: 19.4 %Monroe County: 19.8 %Montgomery County: 18.7 %Neshoba County: 21.3 %Newton County: 20.3 %Noxubee County: 17.9 %Oktibbeha County: 20.1 %Panola County: 20.1 %Pearl River County: 21.1 %Perry County: 21.1 %Pike County: 19.3 %Pontotoc County: 20.9 %Prentiss County: 21.6 %Quitman County: 18.5 %Rankin County: 19.3 %Scott County: 20 %Sharkey County: 17.6 %Simpson County: 19.7 %Smith County: 20.9 %Stone County: 20.9 %Sunflower County: 17.1 %Tallahatchie County: 18.5 %Tate County: 20 %Tippah County: 21.3 %Tishomingo County: 22.2 %Tunica County: 18.6 %Union County: 21.4 %Walthall County: 19.2 %Warren County: 18.3 %Washington County: 16.9 %Wayne County: 19.7 %Webster County: 20.2 %Wilkinson County: 17 %Winston County: 18.7 %Yalobusha County: 19.5 %Yazoo County: 18.6 %
  • Under 18
  • 18 to 19
  • 19 to 20
  • 20 to 21
  • 21 and over
%, 2023. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Boundaries: U.S. Census Bureau cartographic boundary files.

Top 40 counties, 2023

Tishomingo County: 22.2 %Tishomingo County22.2Alcorn County: 21.9 %Alcorn County21.9George County: 21.6 %George County21.6Prentiss County: 21.6 %Prentiss County21.6Union County: 21.4 %Union County21.4Lamar County: 21.3 %Lamar County21.3Neshoba County: 21.3 %Neshoba County21.3Tippah County: 21.3 %Tippah County21.3Harrison County: 21.1 %Harrison County21.1Itawamba County: 21.1 %Itawamba County21.1Pearl River County: 21.1 %Pearl River County21.1Perry County: 21.1 %Perry County21.1Pontotoc County: 20.9 %Pontotoc County20.9Smith County: 20.9 %Smith County20.9Stone County: 20.9 %Stone County20.9Forrest County: 20.8 %Forrest County20.8Lawrence County: 20.6 %Lawrence County20.6Lafayette County: 20.5 %Lafayette County20.5Marion County: 20.4 %Marion County20.4Newton County: 20.3 %Newton County20.3Clarke County: 20.2 %Clarke County20.2Webster County: 20.2 %Webster County20.2Lee County: 20.1 %Lee County20.1Oktibbeha County: 20.1 %Oktibbeha County20.1Panola County: 20.1 %Panola County20.1Calhoun County: 20 %Calhoun County20Scott County: 20 %Scott County20Tate County: 20 %Tate County20Jones County: 19.9 %Jones County19.9Greene County: 19.8 %Greene County19.8Lincoln County: 19.8 %Lincoln County19.8Monroe County: 19.8 %Monroe County19.8DeSoto County: 19.7 %DeSoto County19.7Hancock County: 19.7 %Hancock County19.7Jackson County: 19.7 %Jackson County19.7Simpson County: 19.7 %Simpson County19.7Wayne County: 19.7 %Wayne County19.7Franklin County: 19.6 %Franklin County19.6Yalobusha County: 19.5 %Yalobusha County19.5Benton County: 19.4 %Benton County19.4Tishomingo County: 22.2 %Tishomingo County22.2Alcorn County: 21.9 %Alcorn County21.9George County: 21.6 %George County21.6Prentiss County: 21.6 %Prentiss County21.6Union County: 21.4 %Union County21.4Lamar County: 21.3 %Lamar County21.3Neshoba County: 21.3 %Neshoba County21.3Tippah County: 21.3 %Tippah County21.3Harrison County: 21.1 %Harrison County21.1Itawamba County: 21.1 %Itawamba County21.1Pearl River County: 21.1 %Pearl River County21.1Perry County: 21.1 %Perry County21.1Pontotoc County: 20.9 %Pontotoc County20.9Smith County: 20.9 %Smith County20.9Stone County: 20.9 %Stone County20.9Forrest County: 20.8 %Forrest County20.8Lawrence County: 20.6 %Lawrence County20.6Lafayette County: 20.5 %Lafayette County20.5Marion County: 20.4 %Marion County20.4Newton County: 20.3 %Newton County20.3Clarke County: 20.2 %Clarke County20.2Webster County: 20.2 %Webster County20.2Lee County: 20.1 %Lee County20.1Oktibbeha County: 20.1 %Oktibbeha County20.1Panola County: 20.1 %Panola County20.1Calhoun County: 20 %Calhoun County20Scott County: 20 %Scott County20Tate County: 20 %Tate County20Jones County: 19.9 %Jones County19.9Greene County: 19.8 %Greene County19.8Lincoln County: 19.8 %Lincoln County19.8Monroe County: 19.8 %Monroe County19.8DeSoto County: 19.7 %DeSoto County19.7Hancock County: 19.7 %Hancock County19.7Jackson County: 19.7 %Jackson County19.7Simpson County: 19.7 %Simpson County19.7Wayne County: 19.7 %Wayne County19.7Franklin County: 19.6 %Franklin County19.6Yalobusha County: 19.5 %Yalobusha County19.5Benton County: 19.4 %Benton County19.4
%. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCounties2023 (%)Change on 2022
1Tishomingo County22.2-1.1 pts
2Alcorn County21.9-0.5 pts
3George County21.6-1.7 pts
3Prentiss County21.6-1.7 pts
5Union County21.4+0.2 pts
6Lamar County21.3-0.8 pts
6Neshoba County21.3-2 pts
6Tippah County21.3-1.4 pts
9Harrison County21.1-2.9 pts
9Itawamba County21.1-2.6 pts
9Pearl River County21.1-1.1 pts
9Perry County21.1-2.5 pts
13Pontotoc County20.9-0.9 pts
13Smith County20.9-1.4 pts
13Stone County20.9-2.6 pts
16Forrest County20.8-1.3 pts
17Lawrence County20.6-1.8 pts
18Lafayette County20.5-2.8 pts
19Marion County20.4-1.4 pts
20Newton County20.3-1.2 pts
21Clarke County20.2-0.4 pts
21Webster County20.2-1.8 pts
23Lee County20.1-1.3 pts
23Oktibbeha County20.1-2.3 pts
23Panola County20.1-0.7 pts
26Calhoun County20-2.6 pts
26Scott County20-2.4 pts
26Tate County20-1 pts
29Jones County19.9-0.4 pts
30Greene County19.8-0.8 pts
30Lincoln County19.8-1.6 pts
30Monroe County19.8-1.9 pts
33DeSoto County19.7-0.5 pts
33Hancock County19.7-3.1 pts
33Jackson County19.7-1.5 pts
33Simpson County19.7-1.9 pts
33Wayne County19.7-1.2 pts
38Franklin County19.6-0.9 pts
39Yalobusha County19.5-1.5 pts
40Benton County19.4-1.6 pts
40Marshall County19.4-1 pts
42Pike County19.3-2 pts
42Rankin County19.3-2.9 pts
44Choctaw County19.2-0.9 pts
44Covington County19.2-2.7 pts
44Grenada County19.2-2.6 pts
44Leake County19.2-1.3 pts
44Walthall County19.2-1.4 pts
49Chickasaw County19.1-1.7 pts
50Amite County19-1.4 pts
50Lowndes County19-0.6 pts
52Bolivar County18.9+0.5 pts
52Copiah County18.9-0.5 pts
54Attala County18.8-1.9 pts
54Lauderdale County18.8-2.7 pts
56Montgomery County18.7-2.5 pts
56Winston County18.7-1.5 pts
58Carroll County18.6-2.2 pts
58Humphreys County18.6-1.6 pts
58Tunica County18.6-1.9 pts
58Yazoo County18.6-1.1 pts
62Quitman County18.5-1.1 pts
62Tallahatchie County18.5-0.2 pts
64Warren County18.3-1.5 pts
65Clay County18.1-1.8 pts
65Jasper County18.1-0.7 pts
67Coahoma County17.9-1.6 pts
67Holmes County17.9-0.8 pts
67Noxubee County17.9-1.1 pts
70Jefferson Davis County17.8-1.2 pts
71Madison County17.7-1.2 pts
72Leflore County17.6-3 pts
72Sharkey County17.6-1.6 pts
74Claiborne County17.5-1.2 pts
75Adams County17.4-1.9 pts
76Hinds County17.3-2 pts
76Kemper County17.3-0.7 pts
78Sunflower County17.1-1.4 pts
79Wilkinson County17-1.1 pts
80Washington County16.9-0.9 pts
81Issaquena County16.8-1.1 pts
82Jefferson County16.5-1.5 pts

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the counties are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence (Counties in Mississippi by depression in adults, local model estimate, 2023) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Mississippi by depression in adults, local model estimate, 2023. Centers for Disease Control and Prevention, 4 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Counties in Mississippi by depression in adults, local model estimate, 2023. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Mississippi by depression in adults, local model estimate, 2023 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties (Accessed: 12 October 2026).

BibTeX
@misc{centers_counties_in_mississippi_by_2023,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Mississippi by depression in adults, local model estimate, 2023}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Mississippi by depression in adults, local model estimate, 2023
PY  - 2025
DA  - 2025/12/04
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  - 
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Questions

Which county has the highest depression in adults, local model estimate?

Tishomingo County, with 22.2% in 2023, according to the Centers for Disease Control and Prevention.

Which county has the lowest depression in adults, local model estimate?

Jefferson County, with 16.5% in 2023.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Counties in Mississippi: more rankings