Data / Rankings / Depression in adults, local model estimate / Counties in Mississippi

Counties in Mississippi by depression in adults, local model estimate

Neshoba County had the highest depression in adults, local model estimate of 82 counties in 2021, at 24.1%. Jefferson County had the lowest, at 17.7%. The median was 21%. Source: the Centers for Disease Control and Prevention.

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Highest24.1Neshoba County
Lowest17.7Jefferson County
Median2182 counties

Map of counties, 2021

Adams County: 19.2 %Alcorn County: 23.7 %Amite County: 20.6 %Attala County: 20.8 %Benton County: 21.8 %Bolivar County: 19.5 %Calhoun County: 22.3 %Carroll County: 20.5 %Chickasaw County: 20.9 %Choctaw County: 21.4 %Claiborne County: 19.8 %Clarke County: 21.3 %Clay County: 19.5 %Coahoma County: 20.1 %Copiah County: 20.3 %Covington County: 21.8 %DeSoto County: 21.5 %Forrest County: 21.4 %Franklin County: 21.3 %George County: 23.4 %Greene County: 22 %Grenada County: 20.4 %Hancock County: 23.3 %Harrison County: 21.9 %Hinds County: 19.2 %Holmes County: 20.4 %Humphreys County: 20.1 %Issaquena County: 19.9 %Itawamba County: 23.4 %Jackson County: 21.9 %Jasper County: 20.3 %Jefferson County: 17.7 %Jefferson Davis County: 19.4 %Jones County: 23 %Kemper County: 18.7 %Lafayette County: 22.6 %Lamar County: 22.4 %Lauderdale County: 20.5 %Lawrence County: 22.1 %Leake County: 20.6 %Lee County: 20.5 %Leflore County: 19.6 %Lincoln County: 21.9 %Lowndes County: 19.5 %Madison County: 18.5 %Marion County: 22.9 %Marshall County: 21 %Monroe County: 21.7 %Montgomery County: 20.8 %Neshoba County: 24.1 %Newton County: 21.6 %Noxubee County: 19.6 %Oktibbeha County: 21 %Panola County: 20 %Pearl River County: 23.1 %Perry County: 23.4 %Pike County: 23.3 %Pontotoc County: 22.7 %Prentiss County: 23.6 %Quitman County: 20.9 %Rankin County: 21 %Scott County: 21.4 %Sharkey County: 18.8 %Simpson County: 22.2 %Smith County: 22.9 %Stone County: 23.7 %Sunflower County: 18.8 %Tallahatchie County: 19.5 %Tate County: 21.3 %Tippah County: 23.9 %Tishomingo County: 24.1 %Tunica County: 19.9 %Union County: 23.5 %Walthall County: 20.4 %Warren County: 19.6 %Washington County: 20 %Wayne County: 21.7 %Webster County: 22.2 %Wilkinson County: 19.5 %Winston County: 19.9 %Yalobusha County: 20.4 %Yazoo County: 19.9 %
  • Under 20
  • 20 to 21
  • 21 to 22
  • 22 to 23
  • 23 and over
%, 2021. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Boundaries: U.S. Census Bureau cartographic boundary files.

Top 40 counties, 2021

Neshoba County: 24.1 %Neshoba County24.1Tishomingo County: 24.1 %Tishomingo County24.1Tippah County: 23.9 %Tippah County23.9Alcorn County: 23.7 %Alcorn County23.7Stone County: 23.7 %Stone County23.7Prentiss County: 23.6 %Prentiss County23.6Union County: 23.5 %Union County23.5George County: 23.4 %George County23.4Itawamba County: 23.4 %Itawamba County23.4Perry County: 23.4 %Perry County23.4Hancock County: 23.3 %Hancock County23.3Pike County: 23.3 %Pike County23.3Pearl River County: 23.1 %Pearl River County23.1Jones County: 23 %Jones County23Marion County: 22.9 %Marion County22.9Smith County: 22.9 %Smith County22.9Pontotoc County: 22.7 %Pontotoc County22.7Lafayette County: 22.6 %Lafayette County22.6Lamar County: 22.4 %Lamar County22.4Calhoun County: 22.3 %Calhoun County22.3Simpson County: 22.2 %Simpson County22.2Webster County: 22.2 %Webster County22.2Lawrence County: 22.1 %Lawrence County22.1Greene County: 22 %Greene County22Harrison County: 21.9 %Harrison County21.9Jackson County: 21.9 %Jackson County21.9Lincoln County: 21.9 %Lincoln County21.9Benton County: 21.8 %Benton County21.8Covington County: 21.8 %Covington County21.8Monroe County: 21.7 %Monroe County21.7Wayne County: 21.7 %Wayne County21.7Newton County: 21.6 %Newton County21.6DeSoto County: 21.5 %DeSoto County21.5Choctaw County: 21.4 %Choctaw County21.4Forrest County: 21.4 %Forrest County21.4Scott County: 21.4 %Scott County21.4Clarke County: 21.3 %Clarke County21.3Franklin County: 21.3 %Franklin County21.3Tate County: 21.3 %Tate County21.3Marshall County: 21 %Marshall County21Neshoba County: 24.1 %Neshoba County24.1Tishomingo County: 24.1 %Tishomingo County24.1Tippah County: 23.9 %Tippah County23.9Alcorn County: 23.7 %Alcorn County23.7Stone County: 23.7 %Stone County23.7Prentiss County: 23.6 %Prentiss County23.6Union County: 23.5 %Union County23.5George County: 23.4 %George County23.4Itawamba County: 23.4 %Itawamba County23.4Perry County: 23.4 %Perry County23.4Hancock County: 23.3 %Hancock County23.3Pike County: 23.3 %Pike County23.3Pearl River County: 23.1 %Pearl River County23.1Jones County: 23 %Jones County23Marion County: 22.9 %Marion County22.9Smith County: 22.9 %Smith County22.9Pontotoc County: 22.7 %Pontotoc County22.7Lafayette County: 22.6 %Lafayette County22.6Lamar County: 22.4 %Lamar County22.4Calhoun County: 22.3 %Calhoun County22.3Simpson County: 22.2 %Simpson County22.2Webster County: 22.2 %Webster County22.2Lawrence County: 22.1 %Lawrence County22.1Greene County: 22 %Greene County22Harrison County: 21.9 %Harrison County21.9Jackson County: 21.9 %Jackson County21.9Lincoln County: 21.9 %Lincoln County21.9Benton County: 21.8 %Benton County21.8Covington County: 21.8 %Covington County21.8Monroe County: 21.7 %Monroe County21.7Wayne County: 21.7 %Wayne County21.7Newton County: 21.6 %Newton County21.6DeSoto County: 21.5 %DeSoto County21.5Choctaw County: 21.4 %Choctaw County21.4Forrest County: 21.4 %Forrest County21.4Scott County: 21.4 %Scott County21.4Clarke County: 21.3 %Clarke County21.3Franklin County: 21.3 %Franklin County21.3Tate County: 21.3 %Tate County21.3Marshall County: 21 %Marshall County21
%. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCounties2021 (%)
1Neshoba County24.1
1Tishomingo County24.1
3Tippah County23.9
4Alcorn County23.7
4Stone County23.7
6Prentiss County23.6
7Union County23.5
8George County23.4
8Itawamba County23.4
8Perry County23.4
11Hancock County23.3
11Pike County23.3
13Pearl River County23.1
14Jones County23
15Marion County22.9
15Smith County22.9
17Pontotoc County22.7
18Lafayette County22.6
19Lamar County22.4
20Calhoun County22.3
21Simpson County22.2
21Webster County22.2
23Lawrence County22.1
24Greene County22
25Harrison County21.9
25Jackson County21.9
25Lincoln County21.9
28Benton County21.8
28Covington County21.8
30Monroe County21.7
30Wayne County21.7
32Newton County21.6
33DeSoto County21.5
34Choctaw County21.4
34Forrest County21.4
34Scott County21.4
37Clarke County21.3
37Franklin County21.3
37Tate County21.3
40Marshall County21
40Oktibbeha County21
40Rankin County21
43Chickasaw County20.9
43Quitman County20.9
45Attala County20.8
45Montgomery County20.8
47Amite County20.6
47Leake County20.6
49Carroll County20.5
49Lauderdale County20.5
49Lee County20.5
52Grenada County20.4
52Holmes County20.4
52Walthall County20.4
52Yalobusha County20.4
56Copiah County20.3
56Jasper County20.3
58Coahoma County20.1
58Humphreys County20.1
60Panola County20
60Washington County20
62Issaquena County19.9
62Tunica County19.9
62Winston County19.9
62Yazoo County19.9
66Claiborne County19.8
67Leflore County19.6
67Noxubee County19.6
67Warren County19.6
70Bolivar County19.5
70Clay County19.5
70Lowndes County19.5
70Tallahatchie County19.5
70Wilkinson County19.5
75Jefferson Davis County19.4
76Adams County19.2
76Hinds County19.2
78Sharkey County18.8
78Sunflower County18.8
80Kemper County18.7
81Madison County18.5
82Jefferson County17.7

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the counties are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence (Counties in Mississippi by depression in adults, local model estimate, 2021) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Mississippi by depression in adults, local model estimate, 2021. Centers for Disease Control and Prevention, 4 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties?period=2021. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Counties in Mississippi by depression in adults, local model estimate, 2021. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties?period=2021.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Mississippi by depression in adults, local model estimate, 2021 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties?period=2021 (Accessed: 12 October 2026).

BibTeX
@misc{centers_counties_in_mississippi_by_2021,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Mississippi by depression in adults, local model estimate, 2021}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties?period=2021. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Mississippi by depression in adults, local model estimate, 2021
PY  - 2025
DA  - 2025/12/04
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties?period=2021
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/mississippi-counties?period=2021.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  -
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Rank Counties in Mississippi by depression in adults, local model estimate using official data, and cite the source.
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Questions

Which county has the highest depression in adults, local model estimate?

Neshoba County, with 24.1% in 2021, according to the Centers for Disease Control and Prevention.

Which county has the lowest depression in adults, local model estimate?

Jefferson County, with 17.7% in 2021.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Counties in Mississippi: more rankings