Drug overdose deaths, 12 months ending in Missouri

Drug overdose deaths, 12 months ending in Missouri was 1,204 in April 2026, according to Centers for Disease Control and Prevention. That is down 9.7% from April 2025. That is the 20th highest of 51 states in April 2026.

April 2026, count1,204 Provisional
Change on April 2025-9.7%
Rank20th of 51US states ranked
Series high2,250March 2023
Series low1,070August 2015

Drug overdose deaths, 12 months ending in Missouri, January 2015 to April 2026

CSVChart (SVG)

1,0001,2501,5001,7502,0002,2502015-012016-092018-052020-012021-092023-052025-012026-042015-01: 1,108 count2015-02: 1,107 count2015-03: 1,092 count2015-04: 1,072 count2015-05: 1,093 count2015-06: 1,116 count2015-07: 1,103 count2015-08: 1,070 count2015-09: 1,081 count2015-10: 1,071 count2015-11: 1,090 count2015-12: 1,087 count2016-01: 1,096 count2016-02: 1,121 count2016-03: 1,129 count2016-04: 1,150 count2016-05: 1,147 count2016-06: 1,157 count2016-07: 1,192 count2016-08: 1,236 count2016-09: 1,247 count2016-10: 1,288 count2016-11: 1,329 count2016-12: 1,386 count2017-01: 1,394 count2017-02: 1,388 count2017-03: 1,415 count2017-04: 1,403 count2017-05: 1,403 count2017-06: 1,403 count2017-07: 1,395 count2017-08: 1,392 count2017-09: 1,421 count2017-10: 1,428 count2017-11: 1,407 count2017-12: 1,398 count2018-01: 1,397 count2018-02: 1,407 count2018-03: 1,407 count2018-04: 1,440 count2018-05: 1,455 count2018-06: 1,495 count2018-07: 1,524 count2018-08: 1,560 count2018-09: 1,566 count2018-10: 1,598 count2018-11: 1,627 count2018-12: 1,635 count2019-01: 1,664 count2019-02: 1,667 count2019-03: 1,673 count2019-04: 1,647 count2019-05: 1,635 count2019-06: 1,582 count2019-07: 1,579 count2019-08: 1,588 count2019-09: 1,596 count2019-10: 1,584 count2019-11: 1,581 count2019-12: 1,603 count2020-01: 1,597 count2020-02: 1,631 count2020-03: 1,655 count2020-04: 1,749 count2020-05: 1,834 count2020-06: 1,897 count2020-07: 1,918 count2020-08: 1,907 count2020-09: 1,900 count2020-10: 1,917 count2020-11: 1,927 count2020-12: 1,915 count2021-01: 1,946 count2021-02: 1,950 count2021-03: 1,977 count2021-04: 2,000 count2021-05: 2,014 count2021-06: 2,039 count2021-07: 2,052 count2021-08: 2,095 count2021-09: 2,127 count2021-10: 2,141 count2021-11: 2,167 count2021-12: 2,195 count2022-01: 2,209 count2022-02: 2,206 count2022-03: 2,201 count2022-04: 2,175 count2022-05: 2,158 count2022-06: 2,153 count2022-07: 2,170 count2022-08: 2,163 count2022-09: 2,181 count2022-10: 2,190 count2022-11: 2,185 count2022-12: 2,212 count2023-01: 2,203 count2023-02: 2,215 count2023-03: 2,250 count2023-04: 2,240 count2023-05: 2,221 count2023-06: 2,192 count2023-07: 2,151 count2023-08: 2,146 count2023-09: 2,110 count2023-10: 2,101 count2023-11: 2,079 count2023-12: 2,014 count2024-01: 1,985 count2024-02: 1,976 count2024-03: 1,894 count2024-04: 1,857 count2024-05: 1,820 count2024-06: 1,807 count2024-07: 1,768 count2024-08: 1,683 count2024-09: 1,625 count2024-10: 1,557 count2024-11: 1,517 count2024-12: 1,482 count2025-01: 1,453 count2025-02: 1,398 count2025-03: 1,379 count2025-04: 1,334 count2025-05: 1,316 count2025-06: 1,290 count2025-07: 1,280 count2025-08: 1,284 count2025-09: 1,280 count2025-10: 1,285 count2025-11: 1,259 count2025-12: 1,238 count2026-01: 1,222 count2026-02: 1,213 count2026-03: 1,209 count2026-04: 1,204 count
count. Source: CDC. Retrieved 2026-10-09, published 2026-09-16.
All 136 values
Periodcount
2026-041,204 Provisional
2026-031,209 Provisional
2026-021,213 Provisional
2026-011,222 Provisional
2025-121,238 Provisional
2025-111,259 Provisional
2025-101,285 Provisional
2025-091,280 Provisional
2025-081,284 Provisional
2025-071,280 Provisional
2025-061,290 Provisional
2025-051,316 Provisional
2025-041,334 Provisional
2025-031,379 Provisional
2025-021,398 Provisional
2025-011,453 Provisional
2024-121,482
2024-111,517
2024-101,557
2024-091,625
2024-081,683
2024-071,768
2024-061,807
2024-051,820
2024-041,857
2024-031,894
2024-021,976
2024-011,985
2023-122,014
2023-112,079
2023-102,101
2023-092,110
2023-082,146
2023-072,151
2023-062,192
2023-052,221
2023-042,240
2023-032,250
2023-022,215
2023-012,203
2022-122,212
2022-112,185
2022-102,190
2022-092,181
2022-082,163
2022-072,170
2022-062,153
2022-052,158
2022-042,175
2022-032,201
2022-022,206
2022-012,209
2021-122,195
2021-112,167
2021-102,141
2021-092,127
2021-082,095
2021-072,052
2021-062,039
2021-052,014
2021-042,000
2021-031,977
2021-021,950
2021-011,946
2020-121,915
2020-111,927
2020-101,917
2020-091,900
2020-081,907
2020-071,918
2020-061,897
2020-051,834
2020-041,749
2020-031,655
2020-021,631
2020-011,597
2019-121,603
2019-111,581
2019-101,584
2019-091,596
2019-081,588
2019-071,579
2019-061,582
2019-051,635
2019-041,647
2019-031,673
2019-021,667
2019-011,664
2018-121,635
2018-111,627
2018-101,598
2018-091,566
2018-081,560
2018-071,524
2018-061,495
2018-051,455
2018-041,440
2018-031,407
2018-021,407
2018-011,397
2017-121,398
2017-111,407
2017-101,428
2017-091,421
2017-081,392
2017-071,395
2017-061,403
2017-051,403
2017-041,403
2017-031,415
2017-021,388
2017-011,394
2016-121,386
2016-111,329
2016-101,288
2016-091,247
2016-081,236
2016-071,192
2016-061,157
2016-051,147
2016-041,150
2016-031,129
2016-021,121
2016-011,096
2015-121,087
2015-111,090
2015-101,071
2015-091,081
2015-081,070
2015-071,103
2015-061,116
2015-051,093
2015-041,072
2015-031,092
2015-021,107
2015-011,108

Compared with United States

PlaceApril 2026
Missouri1,204
United States65,726

Rankings

Definition

Drug overdose deaths that occurred in the area during the 12 months ending in the month shown. The value for March 2026 covers April 2025 through March 2026. Underlying cause of death coded X40 to X44, X60 to X64, X85 or Y10 to Y14 (ICD-10).

United States: CDC National Vital Statistics System provisional counts, as reported, not the predicted counts CDC also publishes. Recent months are incomplete and usually rise as death records arrive; periods without final data are marked provisional. Deaths are counted where they occurred. The national figure covers the 50 states and DC. CDC publishes New York City separately; the New York State value is the sum of New York City and the rest of the state. Consecutive months overlap by 11 months, so they must not be added together.

How to cite

Centers for Disease Control and Prevention (CDC). VSRR Provisional Drug Overdose Death Counts (xkb8-kh2a), reported number of drug overdose deaths, 12 month-ending. https://data.cdc.gov/resource/xkb8-kh2a.json?%24order=%3Aid&%24limit=50000&%24where=indicator%3D%27Number+of+Drug+Overdose+Deaths%27+AND+period%3D%2712+month-ending%27. Retrieved 2026-10-09.

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Questions

What is the drug overdose deaths (12 months) in Missouri?

Drug overdose deaths, 12 months ending in Missouri was 1,204 in April 2026, according to Centers for Disease Control and Prevention. That is down 9.7% from April 2025. That is the 20th highest of 51 states in April 2026.

Where does this figure come from?

Centers for Disease Control and Prevention. VSRR Provisional Drug Overdose Death Counts (xkb8-kh2a), reported number of drug overdose deaths, 12 month-ending. Retrieved by Invokely on 2026-10-09.

What was the highest drug overdose deaths (12 months) in Missouri?

2,250 in March 2023, the highest value since January 2015 in this series.

More statistics for Missouri

All statistics for Missouri