Drug overdose deaths, 12 months ending in Mississippi

Drug overdose deaths, 12 months ending in Mississippi was 413 in April 2026, according to Centers for Disease Control and Prevention. That is down 12.3% from April 2025. That is the 35th highest of 51 states in April 2026.

April 2026, count413 Provisional
Change on April 2025-12.3%
Rank35th of 51US states ranked
Series high746December 2021
Series low273February 2019

Drug overdose deaths, 12 months ending in Mississippi, January 2015 to April 2026

CSVChart (SVG)

2003004005006007008002015-012016-092018-052020-012021-092023-052025-012026-042015-01: 302 count2015-02: 302 count2015-03: 307 count2015-04: 322 count2015-05: 328 count2015-06: 329 count2015-07: 343 count2015-08: 348 count2015-09: 337 count2015-10: 331 count2015-11: 325 count2015-12: 333 count2016-01: 338 count2016-02: 335 count2016-03: 334 count2016-04: 322 count2016-05: 323 count2016-06: 320 count2016-07: 319 count2016-08: 313 count2016-09: 327 count2016-10: 336 count2016-11: 334 count2016-12: 332 count2017-01: 329 count2017-02: 323 count2017-03: 327 count2017-04: 334 count2017-05: 329 count2017-06: 331 count2017-07: 327 count2017-08: 315 count2017-09: 318 count2017-10: 319 count2017-11: 330 count2017-12: 329 count2018-01: 324 count2018-02: 337 count2018-03: 327 count2018-04: 314 count2018-05: 313 count2018-06: 307 count2018-07: 308 count2018-08: 325 count2018-09: 315 count2018-10: 308 count2018-11: 299 count2018-12: 290 count2019-01: 288 count2019-02: 273 count2019-03: 285 count2019-04: 290 count2019-05: 303 count2019-06: 325 count2019-07: 333 count2019-08: 330 count2019-09: 335 count2019-10: 342 count2019-11: 347 count2019-12: 365 count2020-01: 379 count2020-02: 397 count2020-03: 399 count2020-04: 420 count2020-05: 442 count2020-06: 451 count2020-07: 462 count2020-08: 491 count2020-09: 497 count2020-10: 509 count2020-11: 522 count2020-12: 532 count2021-01: 561 count2021-02: 596 count2021-03: 628 count2021-04: 659 count2021-05: 668 count2021-06: 674 count2021-07: 695 count2021-08: 693 count2021-09: 713 count2021-10: 731 count2021-11: 737 count2021-12: 746 count2022-01: 744 count2022-02: 719 count2022-03: 722 count2022-04: 697 count2022-05: 706 count2022-06: 703 count2022-07: 685 count2022-08: 683 count2022-09: 694 count2022-10: 696 count2022-11: 692 count2022-12: 702 count2023-01: 700 count2023-02: 698 count2023-03: 680 count2023-04: 676 count2023-05: 651 count2023-06: 650 count2023-07: 648 count2023-08: 651 count2023-09: 635 count2023-10: 619 count2023-11: 643 count2023-12: 633 count2024-01: 623 count2024-02: 636 count2024-03: 617 count2024-04: 613 count2024-05: 604 count2024-06: 577 count2024-07: 572 count2024-08: 559 count2024-09: 548 count2024-10: 537 count2024-11: 513 count2024-12: 491 count2025-01: 482 count2025-02: 466 count2025-03: 476 count2025-04: 471 count2025-05: 462 count2025-06: 469 count2025-07: 473 count2025-08: 470 count2025-09: 468 count2025-10: 464 count2025-11: 453 count2025-12: 453 count2026-01: 430 count2026-02: 421 count2026-03: 412 count2026-04: 413 count
count. Source: CDC. Retrieved 2026-10-09, published 2026-09-16.
All 136 values
Periodcount
2026-04413 Provisional
2026-03412 Provisional
2026-02421 Provisional
2026-01430 Provisional
2025-12453 Provisional
2025-11453 Provisional
2025-10464 Provisional
2025-09468 Provisional
2025-08470 Provisional
2025-07473 Provisional
2025-06469 Provisional
2025-05462 Provisional
2025-04471 Provisional
2025-03476 Provisional
2025-02466 Provisional
2025-01482 Provisional
2024-12491
2024-11513
2024-10537
2024-09548
2024-08559
2024-07572
2024-06577
2024-05604
2024-04613
2024-03617
2024-02636
2024-01623
2023-12633
2023-11643
2023-10619
2023-09635
2023-08651
2023-07648
2023-06650
2023-05651
2023-04676
2023-03680
2023-02698
2023-01700
2022-12702
2022-11692
2022-10696
2022-09694
2022-08683
2022-07685
2022-06703
2022-05706
2022-04697
2022-03722
2022-02719
2022-01744
2021-12746
2021-11737
2021-10731
2021-09713
2021-08693
2021-07695
2021-06674
2021-05668
2021-04659
2021-03628
2021-02596
2021-01561
2020-12532
2020-11522
2020-10509
2020-09497
2020-08491
2020-07462
2020-06451
2020-05442
2020-04420
2020-03399
2020-02397
2020-01379
2019-12365
2019-11347
2019-10342
2019-09335
2019-08330
2019-07333
2019-06325
2019-05303
2019-04290
2019-03285
2019-02273
2019-01288
2018-12290
2018-11299
2018-10308
2018-09315
2018-08325
2018-07308
2018-06307
2018-05313
2018-04314
2018-03327
2018-02337
2018-01324
2017-12329
2017-11330
2017-10319
2017-09318
2017-08315
2017-07327
2017-06331
2017-05329
2017-04334
2017-03327
2017-02323
2017-01329
2016-12332
2016-11334
2016-10336
2016-09327
2016-08313
2016-07319
2016-06320
2016-05323
2016-04322
2016-03334
2016-02335
2016-01338
2015-12333
2015-11325
2015-10331
2015-09337
2015-08348
2015-07343
2015-06329
2015-05328
2015-04322
2015-03307
2015-02302
2015-01302

Compared with United States

PlaceApril 2026
Mississippi413
United States65,726

Rankings

Definition

Drug overdose deaths that occurred in the area during the 12 months ending in the month shown. The value for March 2026 covers April 2025 through March 2026. Underlying cause of death coded X40 to X44, X60 to X64, X85 or Y10 to Y14 (ICD-10).

United States: CDC National Vital Statistics System provisional counts, as reported, not the predicted counts CDC also publishes. Recent months are incomplete and usually rise as death records arrive; periods without final data are marked provisional. Deaths are counted where they occurred. The national figure covers the 50 states and DC. CDC publishes New York City separately; the New York State value is the sum of New York City and the rest of the state. Consecutive months overlap by 11 months, so they must not be added together.

How to cite

Centers for Disease Control and Prevention (CDC). VSRR Provisional Drug Overdose Death Counts (xkb8-kh2a), reported number of drug overdose deaths, 12 month-ending. https://data.cdc.gov/resource/xkb8-kh2a.json?%24order=%3Aid&%24limit=50000&%24where=indicator%3D%27Number+of+Drug+Overdose+Deaths%27+AND+period%3D%2712+month-ending%27. Retrieved 2026-10-09.

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Questions

What is the drug overdose deaths (12 months) in Mississippi?

Drug overdose deaths, 12 months ending in Mississippi was 413 in April 2026, according to Centers for Disease Control and Prevention. That is down 12.3% from April 2025. That is the 35th highest of 51 states in April 2026.

Where does this figure come from?

Centers for Disease Control and Prevention. VSRR Provisional Drug Overdose Death Counts (xkb8-kh2a), reported number of drug overdose deaths, 12 month-ending. Retrieved by Invokely on 2026-10-09.

What was the highest drug overdose deaths (12 months) in Mississippi?

746 in December 2021, the highest value since January 2015 in this series.

More statistics for Mississippi

All statistics for Mississippi