Counties in South Carolina by depression in adults, local model estimate

Pickens County had the highest depression in adults, local model estimate of 46 counties in 2022, at 25.1%. McCormick County had the lowest, at 17.8%. The median was 20.7%. Source: the Centers for Disease Control and Prevention.

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Highest25.1Pickens County
Median20.746 counties

Map of counties, 2022

Abbeville County: 21.2 %Aiken County: 21.8 %Allendale County: 17.9 %Anderson County: 23.4 %Bamberg County: 19.2 %Barnwell County: 20.5 %Beaufort County: 18.6 %Berkeley County: 21.6 %Calhoun County: 20.2 %Charleston County: 19.2 %Cherokee County: 23.4 %Chester County: 21.7 %Chesterfield County: 20.6 %Clarendon County: 19.6 %Colleton County: 21.4 %Darlington County: 20.9 %Dillon County: 23.6 %Dorchester County: 20.9 %Edgefield County: 20 %Fairfield County: 20.7 %Florence County: 20.2 %Georgetown County: 19.3 %Greenville County: 22.1 %Greenwood County: 23.3 %Hampton County: 20.4 %Horry County: 21.1 %Jasper County: 19.3 %Kershaw County: 20.9 %Lancaster County: 20.4 %Laurens County: 22.8 %Lee County: 20.7 %Lexington County: 19.9 %McCormick County: 17.8 %Marion County: 21.2 %Marlboro County: 20.4 %Newberry County: 21.1 %Oconee County: 23 %Orangeburg County: 19.3 %Pickens County: 25.1 %Richland County: 20.2 %Saluda County: 20.2 %Spartanburg County: 23.8 %Sumter County: 20.1 %Union County: 23.2 %Williamsburg County: 18.5 %York County: 20.2 %
  • Under 19
  • 19 to 20
  • 20 to 21
  • 21 to 23
  • 23 and over
%, 2022. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Boundaries: U.S. Census Bureau cartographic boundary files.

All counties, 2022

Pickens County: 25.1 %Pickens County25.1Spartanburg County: 23.8 %Spartanburg County23.8Dillon County: 23.6 %Dillon County23.6Anderson County: 23.4 %Anderson County23.4Cherokee County: 23.4 %Cherokee County23.4Greenwood County: 23.3 %Greenwood County23.3Union County: 23.2 %Union County23.2Oconee County: 23 %Oconee County23Laurens County: 22.8 %Laurens County22.8Greenville County: 22.1 %Greenville County22.1Aiken County: 21.8 %Aiken County21.8Chester County: 21.7 %Chester County21.7Berkeley County: 21.6 %Berkeley County21.6Colleton County: 21.4 %Colleton County21.4Abbeville County: 21.2 %Abbeville County21.2Marion County: 21.2 %Marion County21.2Horry County: 21.1 %Horry County21.1Newberry County: 21.1 %Newberry County21.1Darlington County: 20.9 %Darlington County20.9Dorchester County: 20.9 %Dorchester County20.9Kershaw County: 20.9 %Kershaw County20.9Fairfield County: 20.7 %Fairfield County20.7Lee County: 20.7 %Lee County20.7Chesterfield County: 20.6 %Chesterfield County20.6Barnwell County: 20.5 %Barnwell County20.5Hampton County: 20.4 %Hampton County20.4Lancaster County: 20.4 %Lancaster County20.4Marlboro County: 20.4 %Marlboro County20.4Calhoun County: 20.2 %Calhoun County20.2Florence County: 20.2 %Florence County20.2Richland County: 20.2 %Richland County20.2Saluda County: 20.2 %Saluda County20.2York County: 20.2 %York County20.2Sumter County: 20.1 %Sumter County20.1Edgefield County: 20 %Edgefield County20Lexington County: 19.9 %Lexington County19.9Clarendon County: 19.6 %Clarendon County19.6Georgetown County: 19.3 %Georgetown County19.3Jasper County: 19.3 %Jasper County19.3Orangeburg County: 19.3 %Orangeburg County19.3Bamberg County: 19.2 %Bamberg County19.2Charleston County: 19.2 %Charleston County19.2Beaufort County: 18.6 %Beaufort County18.6Williamsburg County: 18.5 %Williamsburg County18.5Allendale County: 17.9 %Allendale County17.9McCormick County: 17.8 %McCormick County17.8Pickens County: 25.1 %Pickens County25.1Spartanburg County: 23.8 %Spartanburg County23.8Dillon County: 23.6 %Dillon County23.6Anderson County: 23.4 %Anderson County23.4Cherokee County: 23.4 %Cherokee County23.4Greenwood County: 23.3 %Greenwood County23.3Union County: 23.2 %Union County23.2Oconee County: 23 %Oconee County23Laurens County: 22.8 %Laurens County22.8Greenville County: 22.1 %Greenville County22.1Aiken County: 21.8 %Aiken County21.8Chester County: 21.7 %Chester County21.7Berkeley County: 21.6 %Berkeley County21.6Colleton County: 21.4 %Colleton County21.4Abbeville County: 21.2 %Abbeville County21.2Marion County: 21.2 %Marion County21.2Horry County: 21.1 %Horry County21.1Newberry County: 21.1 %Newberry County21.1Darlington County: 20.9 %Darlington County20.9Dorchester County: 20.9 %Dorchester County20.9Kershaw County: 20.9 %Kershaw County20.9Fairfield County: 20.7 %Fairfield County20.7Lee County: 20.7 %Lee County20.7Chesterfield County: 20.6 %Chesterfield County20.6Barnwell County: 20.5 %Barnwell County20.5Hampton County: 20.4 %Hampton County20.4Lancaster County: 20.4 %Lancaster County20.4Marlboro County: 20.4 %Marlboro County20.4Calhoun County: 20.2 %Calhoun County20.2Florence County: 20.2 %Florence County20.2Richland County: 20.2 %Richland County20.2Saluda County: 20.2 %Saluda County20.2York County: 20.2 %York County20.2Sumter County: 20.1 %Sumter County20.1Edgefield County: 20 %Edgefield County20Lexington County: 19.9 %Lexington County19.9Clarendon County: 19.6 %Clarendon County19.6Georgetown County: 19.3 %Georgetown County19.3Jasper County: 19.3 %Jasper County19.3Orangeburg County: 19.3 %Orangeburg County19.3Bamberg County: 19.2 %Bamberg County19.2Charleston County: 19.2 %Charleston County19.2Beaufort County: 18.6 %Beaufort County18.6Williamsburg County: 18.5 %Williamsburg County18.5Allendale County: 17.9 %Allendale County17.9McCormick County: 17.8 %McCormick County17.8
%. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCounties2022 (%)Change on 2021
1Pickens County25.1+0.6 pts
2Spartanburg County23.8+0.7 pts
3Dillon County23.6+2.4 pts
4Anderson County23.4+1.4 pts
4Cherokee County23.4+1.2 pts
6Greenwood County23.3+2.3 pts
7Union County23.2+0.6 pts
8Oconee County23+1.4 pts
9Laurens County22.8-0.6 pts
10Greenville County22.1+2.4 pts
11Aiken County21.8+1.6 pts
12Chester County21.7+1.1 pts
13Berkeley County21.6+2.8 pts
14Colleton County21.4+1 pts
15Abbeville County21.2-1 pts
15Marion County21.2+2.1 pts
17Horry County21.1+0.1 pts
17Newberry County21.1+0.5 pts
19Darlington County20.9-0.5 pts
19Dorchester County20.9+0.4 pts
19Kershaw County20.90 pts
22Fairfield County20.7+2 pts
22Lee County20.7+2.1 pts
24Chesterfield County20.6+1 pts
25Barnwell County20.5+0.1 pts
26Hampton County20.4+1.2 pts
26Lancaster County20.4-0.6 pts
26Marlboro County20.4+0.3 pts
29Calhoun County20.2+0.5 pts
29Florence County20.2+0.4 pts
29Richland County20.2+0.4 pts
29Saluda County20.2-0.6 pts
29York County20.2-0.4 pts
34Sumter County20.1+0.2 pts
35Edgefield County20+0.3 pts
36Lexington County19.9-2.5 pts
37Clarendon County19.6+0.7 pts
38Georgetown County19.3+0.1 pts
38Jasper County19.3+0.8 pts
38Orangeburg County19.3+0.1 pts
41Bamberg County19.2-0.4 pts
41Charleston County19.20 pts
43Beaufort County18.6+2 pts
44Williamsburg County18.5-0.8 pts
45Allendale County17.9-0.2 pts
46McCormick County17.8+0.7 pts

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the counties are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence (Counties in South Carolina by depression in adults, local model estimate, 2022) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in South Carolina by depression in adults, local model estimate, 2022. Centers for Disease Control and Prevention, 4 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2022. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Counties in South Carolina by depression in adults, local model estimate, 2022. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2022.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in South Carolina by depression in adults, local model estimate, 2022 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2022 (Accessed: 12 October 2026).

BibTeX
@misc{centers_counties_in_south_carolina_2022,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in South Carolina by depression in adults, local model estimate, 2022}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2022. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in South Carolina by depression in adults, local model estimate, 2022
PY  - 2025
DA  - 2025/12/04
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2022
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2022.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  - 
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Rank Counties in South Carolina by depression in adults, local model estimate using official data, and cite the source.
rank_places {"indicator":"adult_depression_rate_modelled","level":"province","within":"South Carolina","limit":10}
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Questions

Which county has the highest depression in adults, local model estimate?

Pickens County, with 25.1% in 2022, according to the Centers for Disease Control and Prevention.

Which county has the lowest depression in adults, local model estimate?

McCormick County, with 17.8% in 2022.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Counties in South Carolina: more rankings