Data / Rankings / Depression in adults, local model estimate / Counties in South Carolina

Counties in South Carolina by depression in adults, local model estimate

Pickens County had the highest depression in adults, local model estimate of 46 counties in 2021, at 24.5%. Beaufort County had the lowest, at 16.6%. The median was 20.2%. Source: the Centers for Disease Control and Prevention.

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Highest24.5Pickens County
Lowest16.6Beaufort County
Median20.246 counties

Map of counties, 2021

Abbeville County: 22.2 %Aiken County: 20.2 %Allendale County: 18.1 %Anderson County: 22 %Bamberg County: 19.6 %Barnwell County: 20.4 %Beaufort County: 16.6 %Berkeley County: 18.8 %Calhoun County: 19.7 %Charleston County: 19.2 %Cherokee County: 22.2 %Chester County: 20.6 %Chesterfield County: 19.6 %Clarendon County: 18.9 %Colleton County: 20.4 %Darlington County: 21.4 %Dillon County: 21.2 %Dorchester County: 20.5 %Edgefield County: 19.7 %Fairfield County: 18.7 %Florence County: 19.8 %Georgetown County: 19.2 %Greenville County: 19.7 %Greenwood County: 21 %Hampton County: 19.2 %Horry County: 21 %Jasper County: 18.5 %Kershaw County: 20.9 %Lancaster County: 21 %Laurens County: 23.4 %Lee County: 18.6 %Lexington County: 22.4 %McCormick County: 17.1 %Marion County: 19.1 %Marlboro County: 20.1 %Newberry County: 20.6 %Oconee County: 21.6 %Orangeburg County: 19.2 %Pickens County: 24.5 %Richland County: 19.8 %Saluda County: 20.8 %Spartanburg County: 23.1 %Sumter County: 19.9 %Union County: 22.6 %Williamsburg County: 19.3 %York County: 20.6 %
  • Under 19
  • 19 to 20
  • 20 to 21
  • 21 to 22
  • 22 and over
%, 2021. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Boundaries: U.S. Census Bureau cartographic boundary files.

All counties, 2021

Pickens County: 24.5 %Pickens County24.5Laurens County: 23.4 %Laurens County23.4Spartanburg County: 23.1 %Spartanburg County23.1Union County: 22.6 %Union County22.6Lexington County: 22.4 %Lexington County22.4Abbeville County: 22.2 %Abbeville County22.2Cherokee County: 22.2 %Cherokee County22.2Anderson County: 22 %Anderson County22Oconee County: 21.6 %Oconee County21.6Darlington County: 21.4 %Darlington County21.4Dillon County: 21.2 %Dillon County21.2Greenwood County: 21 %Greenwood County21Horry County: 21 %Horry County21Lancaster County: 21 %Lancaster County21Kershaw County: 20.9 %Kershaw County20.9Saluda County: 20.8 %Saluda County20.8Chester County: 20.6 %Chester County20.6Newberry County: 20.6 %Newberry County20.6York County: 20.6 %York County20.6Dorchester County: 20.5 %Dorchester County20.5Barnwell County: 20.4 %Barnwell County20.4Colleton County: 20.4 %Colleton County20.4Aiken County: 20.2 %Aiken County20.2Marlboro County: 20.1 %Marlboro County20.1Sumter County: 19.9 %Sumter County19.9Florence County: 19.8 %Florence County19.8Richland County: 19.8 %Richland County19.8Calhoun County: 19.7 %Calhoun County19.7Edgefield County: 19.7 %Edgefield County19.7Greenville County: 19.7 %Greenville County19.7Bamberg County: 19.6 %Bamberg County19.6Chesterfield County: 19.6 %Chesterfield County19.6Williamsburg County: 19.3 %Williamsburg County19.3Charleston County: 19.2 %Charleston County19.2Georgetown County: 19.2 %Georgetown County19.2Hampton County: 19.2 %Hampton County19.2Orangeburg County: 19.2 %Orangeburg County19.2Marion County: 19.1 %Marion County19.1Clarendon County: 18.9 %Clarendon County18.9Berkeley County: 18.8 %Berkeley County18.8Fairfield County: 18.7 %Fairfield County18.7Lee County: 18.6 %Lee County18.6Jasper County: 18.5 %Jasper County18.5Allendale County: 18.1 %Allendale County18.1McCormick County: 17.1 %McCormick County17.1Beaufort County: 16.6 %Beaufort County16.6Pickens County: 24.5 %Pickens County24.5Laurens County: 23.4 %Laurens County23.4Spartanburg County: 23.1 %Spartanburg County23.1Union County: 22.6 %Union County22.6Lexington County: 22.4 %Lexington County22.4Abbeville County: 22.2 %Abbeville County22.2Cherokee County: 22.2 %Cherokee County22.2Anderson County: 22 %Anderson County22Oconee County: 21.6 %Oconee County21.6Darlington County: 21.4 %Darlington County21.4Dillon County: 21.2 %Dillon County21.2Greenwood County: 21 %Greenwood County21Horry County: 21 %Horry County21Lancaster County: 21 %Lancaster County21Kershaw County: 20.9 %Kershaw County20.9Saluda County: 20.8 %Saluda County20.8Chester County: 20.6 %Chester County20.6Newberry County: 20.6 %Newberry County20.6York County: 20.6 %York County20.6Dorchester County: 20.5 %Dorchester County20.5Barnwell County: 20.4 %Barnwell County20.4Colleton County: 20.4 %Colleton County20.4Aiken County: 20.2 %Aiken County20.2Marlboro County: 20.1 %Marlboro County20.1Sumter County: 19.9 %Sumter County19.9Florence County: 19.8 %Florence County19.8Richland County: 19.8 %Richland County19.8Calhoun County: 19.7 %Calhoun County19.7Edgefield County: 19.7 %Edgefield County19.7Greenville County: 19.7 %Greenville County19.7Bamberg County: 19.6 %Bamberg County19.6Chesterfield County: 19.6 %Chesterfield County19.6Williamsburg County: 19.3 %Williamsburg County19.3Charleston County: 19.2 %Charleston County19.2Georgetown County: 19.2 %Georgetown County19.2Hampton County: 19.2 %Hampton County19.2Orangeburg County: 19.2 %Orangeburg County19.2Marion County: 19.1 %Marion County19.1Clarendon County: 18.9 %Clarendon County18.9Berkeley County: 18.8 %Berkeley County18.8Fairfield County: 18.7 %Fairfield County18.7Lee County: 18.6 %Lee County18.6Jasper County: 18.5 %Jasper County18.5Allendale County: 18.1 %Allendale County18.1McCormick County: 17.1 %McCormick County17.1Beaufort County: 16.6 %Beaufort County16.6
%. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCounties2021 (%)
1Pickens County24.5
2Laurens County23.4
3Spartanburg County23.1
4Union County22.6
5Lexington County22.4
6Abbeville County22.2
6Cherokee County22.2
8Anderson County22
9Oconee County21.6
10Darlington County21.4
11Dillon County21.2
12Greenwood County21
12Horry County21
12Lancaster County21
15Kershaw County20.9
16Saluda County20.8
17Chester County20.6
17Newberry County20.6
17York County20.6
20Dorchester County20.5
21Barnwell County20.4
21Colleton County20.4
23Aiken County20.2
24Marlboro County20.1
25Sumter County19.9
26Florence County19.8
26Richland County19.8
28Calhoun County19.7
28Edgefield County19.7
28Greenville County19.7
31Bamberg County19.6
31Chesterfield County19.6
33Williamsburg County19.3
34Charleston County19.2
34Georgetown County19.2
34Hampton County19.2
34Orangeburg County19.2
38Marion County19.1
39Clarendon County18.9
40Berkeley County18.8
41Fairfield County18.7
42Lee County18.6
43Jasper County18.5
44Allendale County18.1
45McCormick County17.1
46Beaufort County16.6

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the counties are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence (Counties in South Carolina by depression in adults, local model estimate, 2021) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in South Carolina by depression in adults, local model estimate, 2021. Centers for Disease Control and Prevention, 4 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2021. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Counties in South Carolina by depression in adults, local model estimate, 2021. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2021.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in South Carolina by depression in adults, local model estimate, 2021 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2021 (Accessed: 12 October 2026).

BibTeX
@misc{centers_counties_in_south_carolina_2021,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in South Carolina by depression in adults, local model estimate, 2021}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2021. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in South Carolina by depression in adults, local model estimate, 2021
PY  - 2025
DA  - 2025/12/04
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2021
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/south-carolina-counties?period=2021.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  -
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Questions

Which county has the highest depression in adults, local model estimate?

Pickens County, with 24.5% in 2021, according to the Centers for Disease Control and Prevention.

Which county has the lowest depression in adults, local model estimate?

Beaufort County, with 16.6% in 2021.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Counties in South Carolina: more rankings