Data / Rankings / Depression in adults, local model estimate / Counties in Missouri

Counties in Missouri by depression in adults, local model estimate

Lewis County had the highest depression in adults, local model estimate of 115 counties in 2022, at 26.2%. St. Louis County had the lowest, at 21.5%. The median was 24.1%. Source: the Centers for Disease Control and Prevention.

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Highest26.2Lewis County
Lowest21.5St. Louis County
Median24.1115 counties

Map of counties, 2022

Adair County: 24.8 %Andrew County: 21.9 %Atchison County: 23.4 %Audrain County: 25.6 %Barry County: 23.5 %Barton County: 25.3 %Bates County: 23.7 %Benton County: 23.6 %Bollinger County: 25.6 %Boone County: 23.9 %Buchanan County: 22.4 %Butler County: 24.7 %Caldwell County: 24 %Callaway County: 25.4 %Camden County: 22.3 %Cape Girardeau County: 23.7 %Carroll County: 23.6 %Carter County: 25 %Cass County: 23.4 %Cedar County: 24.7 %Chariton County: 21.8 %Christian County: 24.4 %Clark County: 24.9 %Clay County: 22.7 %Clinton County: 23.6 %Cole County: 22.1 %Cooper County: 23.8 %Crawford County: 24.9 %Dade County: 24.7 %Dallas County: 24.6 %Daviess County: 25.1 %DeKalb County: 22.2 %Dent County: 25.2 %Douglas County: 23.5 %Dunklin County: 25.3 %Franklin County: 23.1 %Gasconade County: 23.1 %Gentry County: 24.3 %Greene County: 24 %Grundy County: 24.2 %Harrison County: 23.4 %Henry County: 24.1 %Hickory County: 23.8 %Holt County: 24.1 %Howard County: 23.5 %Howell County: 25.8 %Iron County: 24.4 %Jackson County: 22.7 %Jasper County: 23.8 %Jefferson County: 24.7 %Johnson County: 24.9 %Knox County: 24.9 %Laclede County: 25.2 %Lafayette County: 23.8 %Lawrence County: 24.9 %Lewis County: 26.2 %Lincoln County: 24.1 %Linn County: 25.2 %Livingston County: 23.9 %McDonald County: 25.2 %Macon County: 22.4 %Madison County: 23.5 %Maries County: 25.5 %Marion County: 24.5 %Mercer County: 23.2 %Miller County: 24.1 %Mississippi County: 25 %Moniteau County: 24.5 %Monroe County: 23.4 %Montgomery County: 24.6 %Morgan County: 23.9 %New Madrid County: 23.2 %Newton County: 23 %Nodaway County: 25.3 %Oregon County: 24.7 %Osage County: 23.1 %Ozark County: 24.8 %Pemiscot County: 24.7 %Perry County: 23.1 %Pettis County: 24.7 %Phelps County: 25.2 %Pike County: 23.1 %Platte County: 23 %Polk County: 25.4 %Pulaski County: 24.2 %Putnam County: 22.3 %Ralls County: 22.7 %Randolph County: 24.5 %Ray County: 24.6 %Reynolds County: 24.9 %Ripley County: 26 %St. Charles County: 22.7 %St. Clair County: 23.8 %Ste. Genevieve County: 23.4 %St. Francois County: 25.4 %St. Louis County: 21.5 %Saline County: 23.3 %Schuyler County: 23.7 %Scotland County: 24.4 %Scott County: 23.9 %Shannon County: 25.7 %Shelby County: 23.9 %Stoddard County: 24.4 %Stone County: 23.5 %Sullivan County: 23.4 %Taney County: 23.2 %Texas County: 23.8 %Vernon County: 24.3 %Warren County: 23.8 %Washington County: 24.9 %Wayne County: 24 %Webster County: 24.3 %Worth County: 23.4 %Wright County: 25.3 %St. Louis city: 24.1 %
  • Under 23
  • 23 to 24
  • 24 to 25
  • 25 and over
%, 2022. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Boundaries: U.S. Census Bureau cartographic boundary files.

Top 40 counties, 2022

Lewis County: 26.2 %Lewis County26.2Ripley County: 26 %Ripley County26Howell County: 25.8 %Howell County25.8Shannon County: 25.7 %Shannon County25.7Audrain County: 25.6 %Audrain County25.6Bollinger County: 25.6 %Bollinger County25.6Maries County: 25.5 %Maries County25.5Callaway County: 25.4 %Callaway County25.4Polk County: 25.4 %Polk County25.4St. Francois County: 25.4 %St. Francois County25.4Barton County: 25.3 %Barton County25.3Dunklin County: 25.3 %Dunklin County25.3Nodaway County: 25.3 %Nodaway County25.3Wright County: 25.3 %Wright County25.3Dent County: 25.2 %Dent County25.2Laclede County: 25.2 %Laclede County25.2Linn County: 25.2 %Linn County25.2McDonald County: 25.2 %McDonald County25.2Phelps County: 25.2 %Phelps County25.2Daviess County: 25.1 %Daviess County25.1Carter County: 25 %Carter County25Mississippi County: 25 %Mississippi County25Clark County: 24.9 %Clark County24.9Crawford County: 24.9 %Crawford County24.9Johnson County: 24.9 %Johnson County24.9Knox County: 24.9 %Knox County24.9Lawrence County: 24.9 %Lawrence County24.9Reynolds County: 24.9 %Reynolds County24.9Washington County: 24.9 %Washington County24.9Adair County: 24.8 %Adair County24.8Ozark County: 24.8 %Ozark County24.8Butler County: 24.7 %Butler County24.7Cedar County: 24.7 %Cedar County24.7Dade County: 24.7 %Dade County24.7Jefferson County: 24.7 %Jefferson County24.7Oregon County: 24.7 %Oregon County24.7Pemiscot County: 24.7 %Pemiscot County24.7Pettis County: 24.7 %Pettis County24.7Dallas County: 24.6 %Dallas County24.6Montgomery County: 24.6 %Montgomery County24.6Lewis County: 26.2 %Lewis County26.2Ripley County: 26 %Ripley County26Howell County: 25.8 %Howell County25.8Shannon County: 25.7 %Shannon County25.7Audrain County: 25.6 %Audrain County25.6Bollinger County: 25.6 %Bollinger County25.6Maries County: 25.5 %Maries County25.5Callaway County: 25.4 %Callaway County25.4Polk County: 25.4 %Polk County25.4St. Francois County: 25.4 %St. Francois County25.4Barton County: 25.3 %Barton County25.3Dunklin County: 25.3 %Dunklin County25.3Nodaway County: 25.3 %Nodaway County25.3Wright County: 25.3 %Wright County25.3Dent County: 25.2 %Dent County25.2Laclede County: 25.2 %Laclede County25.2Linn County: 25.2 %Linn County25.2McDonald County: 25.2 %McDonald County25.2Phelps County: 25.2 %Phelps County25.2Daviess County: 25.1 %Daviess County25.1Carter County: 25 %Carter County25Mississippi County: 25 %Mississippi County25Clark County: 24.9 %Clark County24.9Crawford County: 24.9 %Crawford County24.9Johnson County: 24.9 %Johnson County24.9Knox County: 24.9 %Knox County24.9Lawrence County: 24.9 %Lawrence County24.9Reynolds County: 24.9 %Reynolds County24.9Washington County: 24.9 %Washington County24.9Adair County: 24.8 %Adair County24.8Ozark County: 24.8 %Ozark County24.8Butler County: 24.7 %Butler County24.7Cedar County: 24.7 %Cedar County24.7Dade County: 24.7 %Dade County24.7Jefferson County: 24.7 %Jefferson County24.7Oregon County: 24.7 %Oregon County24.7Pemiscot County: 24.7 %Pemiscot County24.7Pettis County: 24.7 %Pettis County24.7Dallas County: 24.6 %Dallas County24.6Montgomery County: 24.6 %Montgomery County24.6
%. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCounties2022 (%)Change on 2021
1Lewis County26.2+1 pts
2Ripley County26-1.2 pts
3Howell County25.8-0.3 pts
4Shannon County25.7+0.5 pts
5Audrain County25.6+0.2 pts
5Bollinger County25.6+0.5 pts
7Maries County25.5+1.6 pts
8Callaway County25.4+1.8 pts
8Polk County25.4+0.5 pts
8St. Francois County25.4-0.2 pts
11Barton County25.3+0.3 pts
11Dunklin County25.30 pts
11Nodaway County25.3+1.7 pts
11Wright County25.3+0.1 pts
15Dent County25.2+0.3 pts
15Laclede County25.2+1.9 pts
15Linn County25.2+1 pts
15McDonald County25.2+0.6 pts
15Phelps County25.2+1.7 pts
20Daviess County25.1+0.3 pts
21Carter County25+1 pts
21Mississippi County25+1 pts
23Clark County24.9+0.3 pts
23Crawford County24.9+1.2 pts
23Johnson County24.9+1 pts
23Knox County24.9+0.6 pts
23Lawrence County24.9+0.1 pts
23Reynolds County24.9+0.6 pts
23Washington County24.9+0.2 pts
30Adair County24.8-2.3 pts
30Ozark County24.8-0.3 pts
32Butler County24.7-0.6 pts
32Cedar County24.7+0.5 pts
32Dade County24.70 pts
32Jefferson County24.7+0.3 pts
32Oregon County24.7-1.5 pts
32Pemiscot County24.70 pts
32Pettis County24.7-1.2 pts
39Dallas County24.6-0.5 pts
39Montgomery County24.6+0.7 pts
39Ray County24.6+0.8 pts
42Marion County24.5+0.7 pts
42Moniteau County24.5+1.2 pts
42Randolph County24.5-0.6 pts
45Christian County24.4+0.5 pts
45Iron County24.4-0.7 pts
45Scotland County24.4-0.1 pts
45Stoddard County24.4-1 pts
49Gentry County24.3+1.7 pts
49Vernon County24.30 pts
49Webster County24.3-1.2 pts
52Grundy County24.2+0.2 pts
52Pulaski County24.20 pts
54Henry County24.1-1 pts
54Holt County24.1+1.3 pts
54Lincoln County24.1-0.6 pts
54Miller County24.1+0.5 pts
54St. Louis city24.1-1.7 pts
59Caldwell County24+0.6 pts
59Greene County24-1.9 pts
59Wayne County24-2.5 pts
62Boone County23.9-1.8 pts
62Livingston County23.9-1 pts
62Morgan County23.9-0.5 pts
62Scott County23.90 pts
62Shelby County23.9-0.4 pts
67Cooper County23.8-0.1 pts
67Hickory County23.8+0.5 pts
67Jasper County23.8-2 pts
67Lafayette County23.8+1.1 pts
67St. Clair County23.8-0.1 pts
67Texas County23.80 pts
67Warren County23.8+0.9 pts
74Bates County23.7-0.9 pts
74Cape Girardeau County23.7-1.1 pts
74Schuyler County23.7+0.2 pts
77Benton County23.6+2.4 pts
77Carroll County23.60 pts
77Clinton County23.6+1.2 pts
80Barry County23.5-0.5 pts
80Douglas County23.5+0.3 pts
80Howard County23.5-0.1 pts
80Madison County23.5-1.1 pts
80Stone County23.5+0.8 pts
85Atchison County23.40 pts
85Cass County23.4+0.5 pts
85Harrison County23.4-0.5 pts
85Monroe County23.4-0.7 pts
85Ste. Genevieve County23.4-0.6 pts
85Sullivan County23.4-0.1 pts
85Worth County23.4+0.5 pts
92Saline County23.3+0.3 pts
93Mercer County23.2-0.6 pts
93New Madrid County23.2-1.6 pts
93Taney County23.2-1.1 pts
96Franklin County23.1-0.9 pts
96Gasconade County23.1+0.2 pts
96Osage County23.1-0.4 pts
96Perry County23.1-1.5 pts
96Pike County23.1+0.9 pts
101Newton County23-1.6 pts
101Platte County23+1 pts
103Clay County22.7+0.2 pts
103Jackson County22.7+1 pts
103Ralls County22.7-0.7 pts
103St. Charles County22.7-0.2 pts
107Buchanan County22.4-3.8 pts
107Macon County22.4-0.4 pts
109Camden County22.3-0.5 pts
109Putnam County22.3-0.7 pts
111DeKalb County22.2+0.2 pts
112Cole County22.1-0.1 pts
113Andrew County21.9-0.2 pts
114Chariton County21.8+0.7 pts
115St. Louis County21.5+0.7 pts

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the counties are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence (Counties in Missouri by depression in adults, local model estimate, 2022) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Missouri by depression in adults, local model estimate, 2022. Centers for Disease Control and Prevention, 4 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2022. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Counties in Missouri by depression in adults, local model estimate, 2022. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2022.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Missouri by depression in adults, local model estimate, 2022 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2022 (Accessed: 12 October 2026).

BibTeX
@misc{centers_counties_in_missouri_by_2022,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Missouri by depression in adults, local model estimate, 2022}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2022. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Missouri by depression in adults, local model estimate, 2022
PY  - 2025
DA  - 2025/12/04
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2022
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2022.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  -
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Questions

Which county has the highest depression in adults, local model estimate?

Lewis County, with 26.2% in 2022, according to the Centers for Disease Control and Prevention.

Which county has the lowest depression in adults, local model estimate?

St. Louis County, with 21.5% in 2022.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Counties in Missouri: more rankings