Data / Rankings / Depression in adults, local model estimate / Counties in Missouri

Counties in Missouri by depression in adults, local model estimate

Ripley County had the highest depression in adults, local model estimate of 115 counties in 2021, at 27.2%. St. Louis County had the lowest, at 20.8%. The median was 24%. Source: the Centers for Disease Control and Prevention.

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Highest27.2Ripley County
Lowest20.8St. Louis County
Median24115 counties

Map of counties, 2021

Adair County: 27.1 %Andrew County: 22.1 %Atchison County: 23.4 %Audrain County: 25.4 %Barry County: 24 %Barton County: 25 %Bates County: 24.6 %Benton County: 21.2 %Bollinger County: 25.1 %Boone County: 25.7 %Buchanan County: 26.2 %Butler County: 25.3 %Caldwell County: 23.4 %Callaway County: 23.6 %Camden County: 22.8 %Cape Girardeau County: 24.8 %Carroll County: 23.6 %Carter County: 24 %Cass County: 22.9 %Cedar County: 24.2 %Chariton County: 21.1 %Christian County: 23.9 %Clark County: 24.6 %Clay County: 22.5 %Clinton County: 22.4 %Cole County: 22.2 %Cooper County: 23.9 %Crawford County: 23.7 %Dade County: 24.7 %Dallas County: 25.1 %Daviess County: 24.8 %DeKalb County: 22 %Dent County: 24.9 %Douglas County: 23.2 %Dunklin County: 25.3 %Franklin County: 24 %Gasconade County: 22.9 %Gentry County: 22.6 %Greene County: 25.9 %Grundy County: 24 %Harrison County: 23.9 %Henry County: 25.1 %Hickory County: 23.3 %Holt County: 22.8 %Howard County: 23.6 %Howell County: 26.1 %Iron County: 25.1 %Jackson County: 21.7 %Jasper County: 25.8 %Jefferson County: 24.4 %Johnson County: 23.9 %Knox County: 24.3 %Laclede County: 23.3 %Lafayette County: 22.7 %Lawrence County: 24.8 %Lewis County: 25.2 %Lincoln County: 24.7 %Linn County: 24.2 %Livingston County: 24.9 %McDonald County: 24.6 %Macon County: 22.8 %Madison County: 24.6 %Maries County: 23.9 %Marion County: 23.8 %Mercer County: 23.8 %Miller County: 23.6 %Mississippi County: 24 %Moniteau County: 23.3 %Monroe County: 24.1 %Montgomery County: 23.9 %Morgan County: 24.4 %New Madrid County: 24.8 %Newton County: 24.6 %Nodaway County: 23.6 %Oregon County: 26.2 %Osage County: 23.5 %Ozark County: 25.1 %Pemiscot County: 24.7 %Perry County: 24.6 %Pettis County: 25.9 %Phelps County: 23.5 %Pike County: 22.2 %Platte County: 22 %Polk County: 24.9 %Pulaski County: 24.2 %Putnam County: 23 %Ralls County: 23.4 %Randolph County: 25.1 %Ray County: 23.8 %Reynolds County: 24.3 %Ripley County: 27.2 %St. Charles County: 22.9 %St. Clair County: 23.9 %Ste. Genevieve County: 24 %St. Francois County: 25.6 %St. Louis County: 20.8 %Saline County: 23 %Schuyler County: 23.5 %Scotland County: 24.5 %Scott County: 23.9 %Shannon County: 25.2 %Shelby County: 24.3 %Stoddard County: 25.4 %Stone County: 22.7 %Sullivan County: 23.5 %Taney County: 24.3 %Texas County: 23.8 %Vernon County: 24.3 %Warren County: 22.9 %Washington County: 24.7 %Wayne County: 26.5 %Webster County: 25.5 %Worth County: 22.9 %Wright County: 25.2 %St. Louis city: 25.8 %
  • Under 23
  • 23 to 24
  • 24 to 25
  • 25 and over
%, 2021. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Boundaries: U.S. Census Bureau cartographic boundary files.

Top 40 counties, 2021

Ripley County: 27.2 %Ripley County27.2Adair County: 27.1 %Adair County27.1Wayne County: 26.5 %Wayne County26.5Buchanan County: 26.2 %Buchanan County26.2Oregon County: 26.2 %Oregon County26.2Howell County: 26.1 %Howell County26.1Greene County: 25.9 %Greene County25.9Pettis County: 25.9 %Pettis County25.9Jasper County: 25.8 %Jasper County25.8St. Louis city: 25.8 %St. Louis city25.8Boone County: 25.7 %Boone County25.7St. Francois County: 25.6 %St. Francois County25.6Webster County: 25.5 %Webster County25.5Audrain County: 25.4 %Audrain County25.4Stoddard County: 25.4 %Stoddard County25.4Butler County: 25.3 %Butler County25.3Dunklin County: 25.3 %Dunklin County25.3Lewis County: 25.2 %Lewis County25.2Shannon County: 25.2 %Shannon County25.2Wright County: 25.2 %Wright County25.2Bollinger County: 25.1 %Bollinger County25.1Dallas County: 25.1 %Dallas County25.1Henry County: 25.1 %Henry County25.1Iron County: 25.1 %Iron County25.1Ozark County: 25.1 %Ozark County25.1Randolph County: 25.1 %Randolph County25.1Barton County: 25 %Barton County25Dent County: 24.9 %Dent County24.9Livingston County: 24.9 %Livingston County24.9Polk County: 24.9 %Polk County24.9Cape Girardeau County: 24.8 %Cape Girardeau County24.8Daviess County: 24.8 %Daviess County24.8Lawrence County: 24.8 %Lawrence County24.8New Madrid County: 24.8 %New Madrid County24.8Dade County: 24.7 %Dade County24.7Lincoln County: 24.7 %Lincoln County24.7Pemiscot County: 24.7 %Pemiscot County24.7Washington County: 24.7 %Washington County24.7Bates County: 24.6 %Bates County24.6Clark County: 24.6 %Clark County24.6Ripley County: 27.2 %Ripley County27.2Adair County: 27.1 %Adair County27.1Wayne County: 26.5 %Wayne County26.5Buchanan County: 26.2 %Buchanan County26.2Oregon County: 26.2 %Oregon County26.2Howell County: 26.1 %Howell County26.1Greene County: 25.9 %Greene County25.9Pettis County: 25.9 %Pettis County25.9Jasper County: 25.8 %Jasper County25.8St. Louis city: 25.8 %St. Louis city25.8Boone County: 25.7 %Boone County25.7St. Francois County: 25.6 %St. Francois County25.6Webster County: 25.5 %Webster County25.5Audrain County: 25.4 %Audrain County25.4Stoddard County: 25.4 %Stoddard County25.4Butler County: 25.3 %Butler County25.3Dunklin County: 25.3 %Dunklin County25.3Lewis County: 25.2 %Lewis County25.2Shannon County: 25.2 %Shannon County25.2Wright County: 25.2 %Wright County25.2Bollinger County: 25.1 %Bollinger County25.1Dallas County: 25.1 %Dallas County25.1Henry County: 25.1 %Henry County25.1Iron County: 25.1 %Iron County25.1Ozark County: 25.1 %Ozark County25.1Randolph County: 25.1 %Randolph County25.1Barton County: 25 %Barton County25Dent County: 24.9 %Dent County24.9Livingston County: 24.9 %Livingston County24.9Polk County: 24.9 %Polk County24.9Cape Girardeau County: 24.8 %Cape Girardeau County24.8Daviess County: 24.8 %Daviess County24.8Lawrence County: 24.8 %Lawrence County24.8New Madrid County: 24.8 %New Madrid County24.8Dade County: 24.7 %Dade County24.7Lincoln County: 24.7 %Lincoln County24.7Pemiscot County: 24.7 %Pemiscot County24.7Washington County: 24.7 %Washington County24.7Bates County: 24.6 %Bates County24.6Clark County: 24.6 %Clark County24.6
%. Source: CDC, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Full ranking

RankCounties2021 (%)
1Ripley County27.2
2Adair County27.1
3Wayne County26.5
4Buchanan County26.2
4Oregon County26.2
6Howell County26.1
7Greene County25.9
7Pettis County25.9
9Jasper County25.8
9St. Louis city25.8
11Boone County25.7
12St. Francois County25.6
13Webster County25.5
14Audrain County25.4
14Stoddard County25.4
16Butler County25.3
16Dunklin County25.3
18Lewis County25.2
18Shannon County25.2
18Wright County25.2
21Bollinger County25.1
21Dallas County25.1
21Henry County25.1
21Iron County25.1
21Ozark County25.1
21Randolph County25.1
27Barton County25
28Dent County24.9
28Livingston County24.9
28Polk County24.9
31Cape Girardeau County24.8
31Daviess County24.8
31Lawrence County24.8
31New Madrid County24.8
35Dade County24.7
35Lincoln County24.7
35Pemiscot County24.7
35Washington County24.7
39Bates County24.6
39Clark County24.6
39Madison County24.6
39McDonald County24.6
39Newton County24.6
39Perry County24.6
45Scotland County24.5
46Jefferson County24.4
46Morgan County24.4
48Knox County24.3
48Reynolds County24.3
48Shelby County24.3
48Taney County24.3
48Vernon County24.3
53Cedar County24.2
53Linn County24.2
53Pulaski County24.2
56Monroe County24.1
57Barry County24
57Carter County24
57Franklin County24
57Grundy County24
57Mississippi County24
57Ste. Genevieve County24
63Christian County23.9
63Cooper County23.9
63Harrison County23.9
63Johnson County23.9
63Maries County23.9
63Montgomery County23.9
63Scott County23.9
63St. Clair County23.9
71Marion County23.8
71Mercer County23.8
71Ray County23.8
71Texas County23.8
75Crawford County23.7
76Callaway County23.6
76Carroll County23.6
76Howard County23.6
76Miller County23.6
76Nodaway County23.6
81Osage County23.5
81Phelps County23.5
81Schuyler County23.5
81Sullivan County23.5
85Atchison County23.4
85Caldwell County23.4
85Ralls County23.4
88Hickory County23.3
88Laclede County23.3
88Moniteau County23.3
91Douglas County23.2
92Putnam County23
92Saline County23
94Cass County22.9
94Gasconade County22.9
94St. Charles County22.9
94Warren County22.9
94Worth County22.9
99Camden County22.8
99Holt County22.8
99Macon County22.8
102Lafayette County22.7
102Stone County22.7
104Gentry County22.6
105Clay County22.5
106Clinton County22.4
107Cole County22.2
107Pike County22.2
109Andrew County22.1
110DeKalb County22
110Platte County22
112Jackson County21.7
113Benton County21.2
114Chariton County21.1
115St. Louis County20.8

Other periods

About this ranking

Percentage of adults who have ever been told by a doctor, nurse or other health professional that they had a depressive disorder. Model-based estimate for adults aged 18 and over from CDC PLACES. Crude prevalence, not age-adjusted.

US counties and cities (incorporated places of 10,000 or more). CDC PLACES combines Behavioral Risk Factor Surveillance System (BRFSS) answers with local population data through multilevel regression and poststratification, so a county or city value is a model estimate, not a survey count. The year is the BRFSS survey year, not the release year. CDC says the method does not support tracking change in a place over time, and each annual release can change the model, so values for different years are not strictly comparable. A state is missing in a year when its BRFSS data did not meet standards (Kentucky and Pennsylvania in 2023, Florida in 2021). Connecticut counties appear as its nine planning regions from 2022; its eight former counties are not served. City values for 2021 come from the 2023 release, built on 2010 Census place boundaries; later years use 2020 boundaries.

Every value in the ranking comes from the same publisher and the same period, so the counties are compared on one definition. Equal values share a rank.

How to cite

Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

Centers for Disease Control and Prevention. (2025). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence (Counties in Missouri by depression in adults, local model estimate, 2021) [Data set]. Retrieved October 12, 2026, from https://www.cdc.gov/places/

MLA 9

PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Missouri by depression in adults, local model estimate, 2021. Centers for Disease Control and Prevention, 4 Dec. 2025, https://www.cdc.gov/places/. Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2021. Accessed 12 Oct. 2026.

Chicago (author-date)

Centers for Disease Control and Prevention. 2025. PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Counties in Missouri by depression in adults, local model estimate, 2021. Dataset. Accessed October 12, 2026. https://www.cdc.gov/places/. Also distributed by Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2021.

Harvard

Centers for Disease Control and Prevention (2025) PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence, Counties in Missouri by depression in adults, local model estimate, 2021 [Dataset]. Available at: https://www.cdc.gov/places/, via Invokely: https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2021 (Accessed: 12 October 2026).

BibTeX
@misc{centers_counties_in_missouri_by_2021,
  author = {{Centers for Disease Control and Prevention}},
  title = {{PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Missouri by depression in adults, local model estimate, 2021}},
  year = {2025},
  howpublished = {Data set},
  url = {https://www.cdc.gov/places/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2021. Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.},
}
RIS
TY  - DATA
AU  - Centers for Disease Control and Prevention
TI  - PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence: Counties in Missouri by depression in adults, local model estimate, 2021
PY  - 2025
DA  - 2025/12/04
PB  - Centers for Disease Control and Prevention
DB  - Invokely
UR  - https://www.cdc.gov/places/
L2  - https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2021
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/rankings/adult-depression-rate-county-estimate/missouri-counties?period=2021.
N1  - Publisher attribution: Centers for Disease Control and Prevention (CDC). PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. https://www.cdc.gov/places/. Retrieved 2026-10-12. These data are available free from CDC. Use does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
ER  -
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Rank Counties in Missouri by depression in adults, local model estimate using official data, and cite the source.
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Questions

Which county has the highest depression in adults, local model estimate?

Ripley County, with 27.2% in 2021, according to the Centers for Disease Control and Prevention.

Which county has the lowest depression in adults, local model estimate?

St. Louis County, with 20.8% in 2021.

Where does this ranking come from?

Every value comes from one source and one period, so the places are comparable: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, County Data (swc5-untb, fu4u-a9bh, h3ej-a9ec and later releases), depression in adults, crude prevalence. Retrieved 2026-10-12.

Depression in adults, local model estimate: other rankings

Counties in Missouri: more rankings