Population in Cape Girardeau, MO

Population in Cape Girardeau, MO was 40,977 in 2025, according to the U.S. Census Bureau. That is up 0.6% from 2024. That is the 17th highest of 81 cities in 2025.

2025, persons40,977
Change on 2024+0.6%
Series high40,9772025
Series low39,7742020

Next release: Friday, 14 May 2027, estimated by Invokely from past publication dates (low confidence), not announced by the publisher. Release calendar

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Population in Cape Girardeau, MO, 2020 to 2025

39.8K40K40.3K40.5K40.8K41K2020202120222023202420252020: 39,774 persons2021: 40,005 persons2022: 40,388 persons2023: 40,502 persons2024: 40,723 persons2025: 40,977 persons
persons. Source: U.S. Census Bureau, Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals). Retrieved 2026-10-12, published 2026-05-14.
All 6 values
Periodpersons
202540,977
202440,723
202340,502
202240,388
202140,005
202039,774

Compared with Missouri and United States

Place2025
Cape Girardeau, MO40,977
Missouri6,270,541
United States341,784,857

Rankings

Definition

Resident population. Spain and the EU: 1 January, with Spanish figures from the official municipal register (Padrón). Norway: Statistics Norway, 1 January. Iceland and its municipalities: Statistics Iceland, 1 January. United States: Census Bureau population estimates for 1 July. United Kingdom regions and local authorities: Office for National Statistics estimates for 30 June. Other countries and the World: World Bank mid-year estimates, which count all residents regardless of legal status or citizenship. UN World Population Prospects estimates for 1 July cover the years before 1960 and the areas the World Bank does not publish, such as Taiwan.

The World Bank series exists for every country, so use it (through compare) to rank countries on one basis.

How to cite

U.S. Census Bureau. Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals). https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/. Retrieved 2026-10-12.

Citation styles

The publisher is the author. Invokely is named only as the place the figures were read, where a style asks for it.

APA 7

U.S. Census Bureau. (2026). Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals) (Population, Cape Girardeau, MO, 2020 to 2025) [Data set]. Retrieved October 12, 2026, from https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/

MLA 9

Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals), Population, Cape Girardeau, MO, 2020 to 2025. U.S. Census Bureau, 14 May 2026, https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/. Invokely, https://invokely.ai/en/population/cape-girardeau-mo. Accessed 12 Oct. 2026.

Chicago (author-date)

U.S. Census Bureau. 2026. Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals). Population, Cape Girardeau, MO, 2020 to 2025. Dataset. Accessed October 12, 2026. https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/. Also distributed by Invokely, https://invokely.ai/en/population/cape-girardeau-mo.

Harvard

U.S. Census Bureau (2026) Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals), Population, Cape Girardeau, MO, 2020 to 2025 [Dataset]. Available at: https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/, via Invokely: https://invokely.ai/en/population/cape-girardeau-mo (Accessed: 12 October 2026).

BibTeX
@misc{census_population_cape_girardeau_mo_2025,
  author = {{U.S. Census Bureau}},
  title = {{Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals): Population, Cape Girardeau, MO, 2020 to 2025}},
  year = {2026},
  howpublished = {Data set},
  url = {https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/},
  urldate = {2026-10-12},
  note = {Accessed via Invokely, https://invokely.ai/en/population/cape-girardeau-mo. Publisher attribution: U.S. Census Bureau. Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals). https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/. Retrieved 2026-10-12.},
}
RIS
TY  - DATA
AU  - U.S. Census Bureau
TI  - Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals): Population, Cape Girardeau, MO, 2020 to 2025
PY  - 2026
DA  - 2026/05/14
PB  - U.S. Census Bureau
DB  - Invokely
UR  - https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/
L2  - https://invokely.ai/en/population/cape-girardeau-mo
Y2  - 2026/10/12
N1  - Accessed via Invokely, https://invokely.ai/en/population/cape-girardeau-mo.
N1  - Publisher attribution: U.S. Census Bureau. Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals). https://www2.census.gov/programs-surveys/popest/datasets/2020-2025/. Retrieved 2026-10-12.
ER  - 
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Questions

What is the population in Cape Girardeau, MO?

Population in Cape Girardeau, MO was 40,977 in 2025, according to the U.S. Census Bureau. That is up 0.6% from 2024. That is the 17th highest of 81 cities in 2025.

Where does this figure come from?

U.S. Census Bureau. Annual estimates of the resident population for incorporated places, 1 July (Population Estimates Program, subcounty totals). Retrieved by Invokely on 2026-10-12.

What was the highest population in Cape Girardeau, MO?

40,977 in 2025, the highest value since 2020 in this series.

Population elsewhere in Missouri

Related statistics for Cape Girardeau, MO

All statistics for Cape Girardeau, MO | Cape Girardeau, MO in figures